Serodiagnosis in pregnant women with toxoplasmosis in Khartoum state- Sudan

Abstract

Background: Approximately one-third of all humanity has been exposed to Toxoplasma gondii, but the seroprevalence varies considerably between countries from less than 10% to more than 90%.

Objectives: To conduct sero-diagnosis on Toxoplasma. gondii in pregnant women in Khartoum state, Sudan.

Methods:  It’s cross-sectional one designed to diagnose toxoplasma gondii in pregnant female. Serum samples for toxoplasmosis was investigated and screened using the Toxo-latex test, Ict for toxoplasmosis and ELISA

 Results: The results showed 90(30%) serum samples were positive by the routine latex agglutination test while ICT and ELISA detected 46(15.3%) and 68 (22.6%) positive cases respectively. 65(21.7%) serum samples were found to have IgG while IgM was showed only 3(1%) IgM. high rate of infection was encountered in age group 21-30 years, and third trimester showed the highest rate of infection. In this study, meat consumption and cat contact have no role in disease transmission as no statistically association. Also no association between T. gondii sero-prevalence and history of miscarriage.

Conclusion: Findings show the need for an integrated control program against toxoplasmosis because the frequency of specific IgM and IgG antibodies is considered high among pregnant women investigated for Toxoplasmosis.